Package: SubtypeDrug
Type: Package
Title: Prioritization of Candidate Cancer Subtype Specific Drugs
Version: 0.1.9
Author: Xudong Han,
  Junwei Han,
  Chonghui Liu
Maintainer: Junwei Han <hanjunwei1981@163.com>
Date: 2024-4-16
Description: A systematic biology tool was developed to prioritize cancer subtype-specific drugs by integrating genetic perturbation, drug action, biological pathway, and cancer subtype. 
    The capabilities of this tool include inferring patient-specific subpathway activity profiles in the context of gene expression profiles with subtype labels, calculating differentially 
    expressed subpathways based on cultured human cells treated with drugs in the 'cMap' (connectivity map) database, prioritizing cancer subtype specific drugs according to drug-disease 
    reverse association score based on subpathway, and visualization of results (Castelo (2013) <doi:10.1186/1471-2105-14-7>; Han et al (2019) <doi:10.1093/bioinformatics/btz894>; Lamb and Justin (2006) <doi:10.1126/science.1132939>). Please cite using <doi:10.1093/bioinformatics/btab011>.
License: GPL (>= 2)
Depends: R (>= 2.10)
Encoding: UTF-8
LazyData: true
BugReports: https://github.com/hanjunwei-lab/SubtypeDrug/issues
RoxygenNote: 7.3.0
Imports:
        BiocGenerics,GSVA,grDevices,graphics,igraph,parallel,pheatmap,rvest,stats,xml2,ChemmineR
Suggests: knitr, rmarkdown, testthat (>= 3.0.0)
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2024-04-17 02:01:28 UTC; 12859
Repository: CRAN
Date/Publication: 2024-04-17 06:40:02 UTC
Built: R 4.5.3; ; 2026-05-04 18:26:27 UTC; windows
